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The Berkeley Center for Structural Biology is supported by the Howard Hughes Medical Institute, Participating Research Team members, and the National Institutes of Health, National Institute of General Medical Sciences, ALS-ENABLE grant P30 GM124169. The Advanced Light Source is a Department of Energy Office of Science User Facility under Contract No. DE-AC02-05CH11231. The Pilatus detector on beamline 2.0.1 was funded under NIH grant S10OD021832. The Pilatus detector on beamline 5.0.1 was funded under NIH grant S10OD026941.